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Pamapimod
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Pamapimod

CAS: 449811-01-2

Ref. TM-T6927

1mg
55.00 €
5mg
118.00 €
10mg
183.00 €
25mg
369.00 €
50mg
595.00 €
100mg
833.00 €
500mg
1,672.00 €
1ml*10 (DMSO)
129.00 €
Estimated delivery in United States, on Thursday 16 May 2024

Product Information

Name:
Pamapimod
Synonyms:
  • R1503, Ro4402257
  • 6-(2,4-Difluorophenoxy)-2-[[3-hydroxy-1-(2-hydroxyethyl)propyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
  • R 1503
  • Ro 4402257
Description:

Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38 gamma isoforms.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
406.38
Formula:
C19H20F2N4O4
Purity:
99.99%
Color/Form:
Solid
InChI:
InChI=1S/C19H20F2N4O4/c1-25-17-11(10-22-19(24-17)23-13(4-6-26)5-7-27)8-16(18(25)28)29-15-3-2-12(20)9-14(15)21/h2-3,8-10,13,26-27H,4-7H2,1H3,(H,22,23,24)
InChI key:
InChIKey=JYYLVUFNAHSSFE-UHFFFAOYSA-N
SMILES:
Cn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(NC(CCO)CCO)nc21
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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