Product Information
- TRAIL-R2 mAb
- AMG 655
- Immunoglobulin G1, anti-(human cytokine receptor DR5 (death receptor 5)) (human monoclonal XG1-048 v w heavy chain), disulfide with human monoclonal XG1-048 v w light chain, dimer
- Immunoglobulin G1, anti-(human TRAIL receptor 2) (human monoclonal XG1-048 v w heavy chain), disulfide with human monoclonal XG1-048 v w light chain, dimer
Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).
Chemical properties
Technical inquiry about: TM-T76787 Conatumumab
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