TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Found 144 products for "TNF".
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Lucatumumab
CAS:Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.Purity:95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:146.15 kDa (Predicted)UCB-9260
CAS:UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Formula:C26H25N5OPurity:98.39% - 98.71%Color and Shape:White SolidMolecular weight:423.5096Enavatuzumab
CAS:Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.Purity:>95%Color and Shape:Transparent LiquidMolecular weight:~150 kDaTeneliximab
CAS:Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.Purity:99.19% (SEC-HPLC) - >95.0% (SDS-PAGE)Color and Shape:LiquidMolecular weight:146.06 kDa (Predicted)Iscalimab
CAS:Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.Purity:>95%Color and Shape:Transparent LiquidMolecular weight:146.08 kDa (Predicted)Conatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Purity:> 95% - > 95%Color and Shape:Transparent LiquidMolecular weight:145.44 kDa (Predicted)Ozoralizumab
CAS:Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Purity:SDS-PAGE:> 95%;SEC-HPLC:95.6%Color and Shape:Transparent LiquidMolecular weight:38.44 kDa (Predicted)Ruplizumab
CAS:PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.Purity:98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.42 kDa (Predicted)HS-243
CAS:HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.Formula:C17H16N4O3Purity:98.62%Color and Shape:SolidMolecular weight:324.3339(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Formula:C27H39N5O7Purity:97.61% - 98.23%Color and Shape:Yellow SolidMolecular weight:545.63Dacetuzumab
CAS:Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.Purity:95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.1 kDa (Predicted)Utomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formula:C17H24N8O3Purity:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:142.77 kDa (Predicted)Anti-Mouse OX40L/CD134L Antibody (RM134L)
Anti-Mouse OX40L/CD134L Antibody (RM134L) attenuates immune response, used in inflammation and cancer research.Purity:95% - 97.6% (SDS-PAGE); 99.5% (SEC-HPLC)Molecular weight:144.63 kDa (Predicted)KGYY15
CAS:KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Formula:C84H129N21O22SColor and Shape:SolidMolecular weight:1817.12Varlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Purity:SDS-PAGE:95% SEC-HPLC:98.65%Color and Shape:Transparent LiquidMolecular weight:146 kDa (Predicted)Tengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Color and Shape:LiquidLenercept
CAS:Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Color and Shape:LiquidIspectamab
Ispectamab is an anti-TNFRSF17 human monoclonal antibody for research on TNFRSF17-associated biology.Molecular weight:~148 kDaRagifilimab
CAS:Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:Transparent LiquidMolecular weight:146.46 kDa (Predicted)TNF-α (46-65), human
CAS:Human TNF alpha (46-65) peptide.Formula:C110H172N24O30Purity:98%Color and Shape:SolidMolecular weight:2310.69
