MAPK-IN-2
Ref. TM-T79572
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 9 Jul 2024
Product Information
Name:
MAPK-IN-2
Description:
MAPK-IN-2 (compound 3h) is an efficacious MAPK inhibitor with antineoplastic properties that significantly hinders proliferation across various cancer cell lines. It demonstrates robust suppression of the MAPK pathway (EGFR WT IC50 = 281 nM, c-MET IC50 = 205 nM, B-RAF WT IC50 = 112 nM, CDK4/6 IC50 = 95 and 184 nM, respectively) and exhibits pronounced activity against mutated forms of EGFR and B-RAF (EGFR T790M IC50 = 69 nM and B-RAF V600E IC50 = 83 nM) [1].
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
380.23
Formula:
C20H11Cl2N3O
Purity:
98%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TM-T79572 MAPK-IN-2
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