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15(R)-Prostaglandin E2

CAS:

Ref. TM-T84587

15(R)-Prostaglandin E2
Targetmol

Product Information

Name:15(R)-Prostaglandin E2
Synonyms:
  • 15-epi PGE2
Brand:Targetmol
Description:15(R)-Prostaglandin E2, the C-15 epimer of the more physiologically abundant 15(S)-PGE2 (sc-201225) isomer, is produced mainly from arachidonic acid (sc-200770) via the action of COX and PGES enzymes. Present in nearly all cell types, PGE2 interacts with four distinct receptors, EP1 to EP4, leading to a wide range of biological effects. However, 15(R)-Prostaglandin E2 exhibits significantly lower efficacy in most biological assays compared to its 15(S) counterpart. Notably, acid catalyzed epimerization can transform 15(R)-Prostaglandin E2 into the more active 15(S)-Prostaglandin E2 form.
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Chemical properties

Molecular weight:352.471
Formula:C20H32O5
Color/Form:Solid

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