Product Information
Name:HVH-2930
Brand:Targetmol
Description:HVH-2930 is an inhibitor of Heat Shock Protein 90 (HSP90). It suppresses the cell viability of BT474 (Trastuzumab sensitive) and JIMT-1 (Trastuzumab resistant) by downregulating HSP90 client proteins such as HER2, p-HER2, AKT, p-AKT, cyclin D1, and survivin, with IC50 values of 6.86 μM and 4.42 μM, respectively. Additionally, HVH-2930 demonstrates antitumor efficacy in a mouse model and exhibits favorable pharmacokinetic properties in vivo.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:488.62
Formula:C29H36N4O3
Color/Form:Solid
Technical inquiry about: HVH-2930
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