Product Information
Name:EGFR-IN-117
Brand:Targetmol
Description:EGFR-IN-117 (Compound 8h) exhibits inhibitory activity against EGFR mutations, specifically targeting the tumor environment and inducing apoptosis in cancer cells. This compound effectively inhibits the proliferation of H1975, PC-9, and mutant EGFR cells including BaF3-EGFRL858R/T790M/C797S and BaF3–C797S/Del19/T790M, with IC50 values of 13 nM, 19 nM, 1.2 nM, and 1.3 nM respectively. Additionally, EGFR-IN-117 demonstrates anti-tumor activity in mouse models.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:572.52
Formula:C25H30BrN7O2S
Color/Form:Solid
Technical inquiry about: EGFR-IN-117
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