Estimated delivery in United States, on Tuesday 4 Mar 2025
Product Information
Name:
LSN3074753
Description:
LSN3074753, a derivative of LY3009120, acts as a pan-RAF and Raf dimer inhibitor. This compound exhibits inhibitory activity against tumor cells driven by either BRAF monomers or RAF dimers, particularly in the activation of the MAPK pathway, including colorectal cancers with BRAF or KRAS mutations. When combined with Cetuximab, LSN3074753 demonstrates additive and synergistic effects in colorectal cancer PDX models, especially in those harboring KRAS or BRAF mutations.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
439.53
Formula:
C24H30FN5O2
Color/Form:
Liquid
MDL:
Melting point:
Boiling point:
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EINECS:
Merck:
HS code:
Technical inquiry about: TM-T89906 LSN3074753
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