LS-106
Ref. TM-T89954
10mg
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50mg
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Product Information
Name:LS-106
Brand:Targetmol
Description:LS-106 is an orally active, effective epidermal growth factor receptor (EGFR) inhibitor displaying antitumor activity both in vitro and in vivo. It inhibits the kinase activities of EGFR19del/T790M/C797S and EGFRL858R/T790M/C797S, with IC50 values of 2.4 nmol/L and 3.1 nmol/L, respectively, demonstrating stronger inhibition than Osimertinib. LS-106 induces cell apoptosis (Apoptosis), suppresses the proliferation of tumor cells carrying EGFR19del/T790M/C797S, and results in significant tumor reduction in a C797S mutant xenograft model.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:548.84
Formula:C24H28BrClN5OP
Color/Form:Solid
Technical inquiry about: LS-106
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