Product Information
Name:Braftide
Brand:Targetmol
Description:Braftide is an allosteric inhibitor of BRAF kinase that exerts its effect by targeting the surface of BRAF kinase dimers, thereby preventing their formation. It inhibits both wild-type BRAF and oncogenic BRAFG469A, with IC50 values of 364 nM and 172 nM, respectively. When combined with the TAT sequence, Braftide can suppress the MAPK signaling pathway, inhibiting the proliferation of KRAS-mutant tumor cells, with EC50 values of 7.1 μM for HCT116 and 6.6 μM for HCT-15.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1243.52
Formula:C57H94N16O13S
Color/Form:Solid
Technical inquiry about: Braftide
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