Product Information
Name:Ac-DMLD-CMK
Brand:Targetmol
Description:Ac-DMLD-CMK is a peptide designed to target the caspase3-Gsdme signaling pathway in mice. It specifically inhibits the activation of caspase 3 and Gsdme, preventing the cleavage of Gsdme by caspase 3, which reduces pyroptosis. This process helps alleviate damage to renal tubular epithelial cells and decrease the secretion of inflammatory cytokines. Ac-DMLD-CMK can lower serum creatinine and blood urea nitrogen levels in mice induced by Cisplatin, thereby mitigating the progression of renal dysfunction. It holds potential for research into chemotherapy-induced nephrotoxicity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:567.053
Formula:C22H35ClN4O9S
Color/Form:Solid
Technical inquiry about: Ac-DMLD-CMK
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