Product Information
Name:2-Amino-6-((2,6-dioxopiperidin-3-yl)carbamoyl)benzoic Acid
Controlled Product
Synonyms:
- Benzoic acid
- 2-amino-6-[[(2,6-dioxo-3-piperidinyl)amino]carbonyl]- (ACI)
- 2-Amino-6-[[(2,6-dioxo-3-piperidinyl)amino]carbonyl]benzoic acid (ACI)
Brand:TRC
Description:
Applications 2-Amino-6-((2,6-dioxopiperidin-3-yl)carbamoyl)benzoic Acid is a metabolite of Pomalidomide, a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:291.259
Formula:C13H13N3O5
Color/Form:Neat
InChI:InChI=1S/C13H13N3O5/c14-7-3-1-2-6(10(7)13(20)21)11(18)15-8-4-5-9(17)16-12(8)19/h1-3,8H,4-5,14H2,(H,15,18)(H,20,21)(H,16,17,19)
InChI key:InChIKey=WUCFRUNKXKEODY-UHFFFAOYSA-N
SMILES:Nc1cccc(C(=O)NC2CCC(=O)NC2=O)c1C(=O)O
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