
CAS 1001852-14-7
:Formula:C13H13N3O5
InChI:InChI=1S/C13H13N3O5/c14-7-3-1-2-6(10(7)13(20)21)11(18)15-8-4-5-9(17)16-12(8)19/h1-3,8H,4-5,14H2,(H,15,18)(H,20,21)(H,16,17,19)
InChI key:WUCFRUNKXKEODY-UHFFFAOYSA-N
SMILES:C1CC(=O)NC(=O)C1NC(=O)C2=C(C(=CC=C2)N)C(=O)O
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Pomalidomide Impurity 11 Triethylamine Salt
CAS:Formula:C13H13N3O5·Et3NColor and Shape:Pale Green SolidMolecular weight:291.26 101.192-Amino-6-((2,6-dioxopiperidin-3-yl)carbamoyl)benzoic Acid
CAS:Controlled ProductApplications 2-Amino-6-((2,6-dioxopiperidin-3-yl)carbamoyl)benzoic Acid is a metabolite of Pomalidomide, a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)Formula:C13H13N3O5Color and Shape:NeatMolecular weight:291.259


