TR-A165620 - 2-4-acetoxy-2-fluoro-biphenyl-4-yl-propionic-acid-methyl-ester | 215175-84-1

Flurbiprofen Axetil

<p>1-(Acetyloxy)ethyl 2-(2-fluorobiphenyl-4-yl)propanoate</p>

<p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>

<p>1-Acetoxyethyl 2-(2-fluoro-4-biphenylyl)propionate is a synthetic analog of flurbiprofen that has potent nonsteroidal anti-inflammatory drug activity. It binds to the same receptor as flurbiprofen, but with a higher affinity. 1-Acetoxyethyl 2-(2-fluoro-4-biphenylyl)propionate is used for the treatment of postoperative pain and inflammation following abdominal surgery. This compound is also used for the prevention of ischemic brain damage after cardiac bypass surgery or other types of vascular surgery, such as carotid endarterectomy. 1-Acetoxyethyl 2-(2-fluoro-4-biphenylyl)propionate can be synthesized by reacting bisphenol A with carbonyldiimidazole and 4-[2-(2,4 -difluorophenyl)-</p>

<p>Applications An anti-inflammatory used as an analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chalmers, et al.: Ann. Rheum. Dis., 31, 319 (1972), Nishizawa, et al.: Thromb. Res., 3, 577 (1973)<br></p>

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