N1-Acetylspermine Trihydrochloride

CAS: 77928-70-2

Ref. TR-A188005

Product Information

• Name: N1-Acetylspermine Trihydrochloride
• Synonyms: N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamide trihydrochloride, acetamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-, N-[3-({4-[(3-Aminopropyl)amino]butyl}amino)propyl]acetamid

Description

Applications N1-Acetylspermine Trihydrochloride is a monoacetylated derivative of Spermine (S680510); a biogenic polyamine formed from Spermidine (S680400) that occurs in almost all tissues. Spermine is also essential for both normal and neoplastic tissue growth and is involved in the modulation of calcium-dependent immune processes.
References Israel, et al.: J. Med. Chem., 7, 710 (1964); Janne, J., et al.: Biochim. Biophys. Acta, 473, 241 (1978); Theoharides, T.C., et al.: Life Sci., 27, 703 (1980); Horn, Y., et al.: Cancer Res., 42, 3248 (1982)

• Brand: TRC

Chemical properties

• Molecular weight: 353.76
• Formula: C₁₂H₃₁Cl₃N₄O
• Color/Form: Neat
• InChI: InChI=1S/C12H28N4O.3ClH/c1-12(17)16-11-5-10-15-8-3-2-7-14-9-4-6-13;;;/h14-15H,2-11,13H2,1H3,(H,16,17);3*1H
• InChI key: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#CCC(=O)c1ccccc1F