Alpha1-24-Adrenocorticotropic-d4 Hormone TFA Salt

CAS: 16960-16-0

Ref. TR-A305292

Product Information

• Name: Alpha1-24-Adrenocorticotropic-d4 Hormone TFA Salt
• Synonyms: α1-24-Corticotropin-d4, (1-24)α-ACTH-d4, 1-24 ACTH-d4 (human), 1-24 corticotropin-d4 (human), 10: PN: WO03051390 PAGE: 52 claimed protein-d4, 1: PN: EP2615103 SEQID: 1 claimed protein-d4, 1: PN: WO2010098079 SEQID: 2 claimed protein-d4, 1: PN: WO2011071155 SEQID: 1 claimed protein-d4, 20: PN: WO2006052468 SEQID: 2 claimed sequence-d4, 2136: PN: WO03060071 SEQID: 2198 unclaimed-d4, 2: PN: US8796416 SEQID: 2 claimed protein-d4, 2: PN: WO2010098079 SEQID: 2 claimed protein-d4, 3: PN: WO2011143152 PAGE: 61 claimed protein-d4, 3: PN: WO2013099762 SEQID: 3 unclaimed protein-d4, 4: PN: WO2004045592 SEQID: 3 unclaimed sequence-d4, 7: PN: US20090175821 SEQID: 7 claimed protein-d4, 8: PN: WO0069900 SEQID: 7 unclaimed sequence-d4, ACTH1-24-d4, ACTHα1-24-d4, Actholain-d4, Adrenocorticotropin(1-24)-d4, Ba 30920-d4, Ba 36716-d4, Corticotropin-(1-24)-d4, Cortrophin S-d4, Cortrosinta-d4, Cortrosyn-d4, Cosyntropin-d4, Human ACTH (1-24)-d4, L-Seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-α-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-d2-L-lysyl-L-prolyl-L-valylglycyl-d2-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-proline, Nuvacthen Depot, PN: WO9952928, EQID: 9 claimed protein-d4, Porcine ACTH (1-24)-d4, Synacthen-d4, Synacthene-d4, Synacthene-retard-d4, Synecthen-d4, Tetracosactid-d4, Tetracosactide-d4, Tetracosactrin-d4, Tetracosapeptide-d4, α1-24-ACTH-d4, β-Corticotrophin-(1-24)-tetracosapeptide-d4, β1-24-ACTH, β1-24-Corticotropin-d4
• Brand: TRC

Description

Applications α1-24-Adrenocorticotropic-d4 Hormone is the labeled analog of α1-24-Adrenocorticotropic Hormone (A305290), which is used in the treatment of West syndrome (WS).
References Munakata, M., et. al.: Tohoku J. Exp. Med., 232, 273 (2014);

Chemical properties

• Molecular weight: 2937.4611402
• Formula: C₁₃₆H₂₀₆D₄N₄₀O₃₁S•x(C₂HF₃O₂)
• Color/Form: Neat
• InChI: InChI=1S/C136H210N40O31S/c1-75(2)109(127(200)154-71-106(181)156-88(31-13-17-52-137)114(187)158-89(32-14-18-53-138)115(188)159-91(35-21-56-149-134(142)143)116(189)164-96(37-23-58-151-136(146)147)131(204)175-60-25-39-104(175)126(199)173-111(77(5)6)128(201)163-90(33-15-19-54-139)120(193)171-110(76(3)4)129(202)169-101(65-80-43-47-84(180)48-44-80)132(205)176-61-26-40-105(176)133(206)207)172-125(198)103-38-24-59-174(103)130(203)95(34-16-20-55-140)157-107(182)70-153-113(186)99(66-81-68-152-87-30-12-11-29-85(81)87)167-117(190)92(36-22-57-150-135(144)145)160-121(194)98(63-78-27-9-8-10-28-78)166-123(196)100(67-82-69-148-74-155-82)168-118(191)93(49-50-108(183)184)161-119(192)94(51-62-208-7)162-124(197)102(73-178)170-122(195)97(165-112(185)86(141)72-177)64-79-41-45-83(179)46-42-79/h8-12,27-30,41-48,68-69,74-77,86,88-105,109-111,152,177-180H,13-26,31-40,49-67,70-73,137-141H2,1-7H3,(H,148,155)(H,153,186)(H,154,200)(H,156,181)(H,157,182)(H,158,187)(H,159,188)(H,160,194)(H,161,192)(H,162,197)(H,163,201)(H,164,189)(H,165,185)(H,166,196)(H,167,190)(H,168,191)(H,169,202)(H,170,195)(H,171,193)(H,172,198)(H,173,199)(H,183,184)(H,206,207)(H4,142,143,149)(H4,144,145,150)(H4,146,147,151)/t86-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99?,100-,101-,102-,103-,104-,105-,109-,110-,111-/m0/s1