Product Information
Name:(R)-Ambrisentan
Synonyms:
- Benzenepropanoic acid
- α-[(4,6-dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-
- (αR)-
- (αR)-α-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoic acid
- Ambrisentan related
- 3109.Z
Brand:TRC
Description:Applications (R)-Ambrisentan is the R-isomer impurity of Ambrisentan (A575860), which is a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996); Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002); Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:378.42
Formula:C22H22N2O4
Color/Form:White To Off-White
InChI:InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m0/s1
InChI key:InChIKey=OUJTZYPIHDYQMC-IBGZPJMESA-N
SMILES:COC(c1ccccc1)(c1ccccc1)[C@@H](Oc1nc(C)cc(C)n1)C(=O)O
Technical inquiry about: (R)-Ambrisentan
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