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6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile
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6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile

CAS: 848139-78-6

Ref. TR-A604050

10mg
243.00 €
100mg
1,643.00 €
Estimated delivery in United States, on Tuesday 18 Feb 2025

Product Information

Name:
6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile
Controlled Product
Synonyms:
  • 4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinoline
  • 6-Amino-4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxyquinoline
  • 3-Quinolinecarbonitrile, 6-amino-4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-ethoxy-
  • 6-Amino-4-(3-Chloro-4-((2-Pyridinyl)Methoxy)Anilino)-3-Cyano-7-Ethoxyquinoline
  • 6-Amino-4-(3-Chloro-4-(Pyridin-2-Ylmethoxy)Phenylamino)-7-Ethoxyquinoline-3-Carbonitrile
  • 6-Amino-4-[[3-Chloro-4-(2-Pyridinylmethoxy)Phenyl]Amino]-7-Ethoxy-3-Quinolinecarbonitrile
Description:

Applications 6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile, is used in the synthetic preparation of aminopropanamides which is used in irreversible inhibition of epidermal growth factor receptor (EGFR) for potential use in cancer therapy.
References Carmi, C., et al.: J. Med. Chem., 55, 2251 (2012)

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
445.9
Formula:
C24H20ClN5O2
Color/Form:
Neat
InChI:
InChI=1S/C9H13NO2/c1-11-8-4-3-7(6-10)5-9(8)12-2/h3-5H,6,10H2,1-2H3
InChI key:
InChIKey=DIVNUTGTTIRPQA-UHFFFAOYSA-N
SMILES:
COc1ccc(CN)cc1OC
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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