2-Aminopyrimidine-5-boronic Acid Pinacol Ester

CAS: 402960-38-7

Ref. TR-A629055

Product Information

• Name: 2-Aminopyrimidine-5-boronic Acid Pinacol Ester
• Synonyms: (2-Aminopyrimidin-5-yl)boronic Acid Pinacol Ester, 2-(2-Aminopyrimidin-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-amine, [5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)pyrimidin-2-yl]amine
• Brand: TRC

Description

Applications 2-Aminopyrimidine-5-boronic Acid Pinacol Ester is used in the preparation of phosphoinositide-3-kinases (PI3K) inhibitors.
References Burger, M.T. et al.: ACS Med. Chem. Lett., 2, 774 (2011); Heffron, T.P. et al.: J. Med. Chdem., 55, 8007 (2012);

Chemical properties

• Molecular weight: 221.06
• Formula: C₁₀H₁₆BN₃O₂
• Color/Form: Neat
• InChI: InChI=1S/C10H16BN3O2/c1-9(2)10(3,4)16-11(15-9)7-5-13-8(12)14-6-7/h5-6H,1-4H3,(H2,12,13,14)
• InChI key: InChIKey=BPQVMIDUTRJYSC-UHFFFAOYSA-N
• SMILES: CC1(C)OB(c2cnc(N)nc2)OC1(C)C