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3-Aminopiperidine-2,6-dione Hydrochloride

CAS:

Ref. TR-A632980

1g
96.00€
5g
169.00€
25g
352.00€
3-Aminopiperidine-2,6-dione Hydrochloride
TRC

Product Information

Name:3-Aminopiperidine-2,6-dione Hydrochloride
Controlled Product
Synonyms:
  • 3-Amino-2,6-piperidinedione Monohydrochloride
  • 2-Amino-glutarimide Hydrochloride
  • 3-Amino-2,6-dioxopiperidine Hydrochloride
  • 3-Amino-2,6-piperidinedione Hydrochloride
  • 3-Aminopiperidine-2,6-dione Monohydrochloride, DL-Glutamic Acid Imide Hydrochloride
  • Glutamimide Hydrochloride
Brand:TRC
Description:Applications 3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.References Kronke, J., et al.: Nature 523, 183 (2015); Liu C., et al.: Faming Zhuanli Shenqing CN 105348257 A 20160224 (2016); Rao, R., et al. : PCT Int. Appl. WO 2016024286 A2 20160218 (2016)
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:164.590
Formula:C5H8N2O2·ClH
Color/Form:Off-White
InChI:InChI=1S/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H/t3-;/m0./s1
InChI key:InChIKey=YCPULGHBTPQLRH-UHFFFAOYSA-N
SMILES:Cl.NC1CCC(=O)NC1=O

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