Atorvastatin Calcium Salt

CAS: 134523-03-8

Ref. TR-A791750

Product Information

• Name: Atorvastatin Calcium Salt
• Synonyms: 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), [R-(R*,R*)]-, Atocor, Atoraz, Atorvastatin calcium, Atorvastatin hemicalcium, Atorvastatin hemicalcium salt, CI 981, Lipitor, Lorvast, Lowlip, Rotacor, Sortis, Storvas, Tahor
• Brand: TRC

Description

Applications A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.
References Zhao Y et al. Medicine (Baltimore). 2017 Feb;96(7):e6104.Wu X et al. Carcinogenesis. 2017 Feb 16Sepehri Z et al. PLoS One. 2017 Feb 13;12(2):e0172404

Chemical properties

• Molecular weight: 1155.34
• Formula: C₃₃H₃₄FN₂O₅·Ca
• Color/Form: Neat
• InChI: InChI=1S/2C33H35FN2O5.Ca/c2*1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;/h2*3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);/q;;+2/p-2/t2*26-,27-;/m11./s1
• SMILES: CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)[O-].CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)[O-].[Ca+2]