3'-Azido-3'-deoxythymidine

CAS: 30516-87-1

Ref. TR-A825000

Product Information

• Name: 3'-Azido-3'-deoxythymidine
• Synonyms: Zidovudine, 1-(3-Azido-2,3-dideoxy-ß-d-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, Zidovudine (GR 63367X), BP Zidovudine and Lamivudine Impurity Standard, 1-(3-Azido-2,3-Dideoxy-Beta-D-Ribofuranosyl)Thymine, 1-(3-azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-(3-azido-2,3-dideoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-(4-Azido-5-Hydroxymethyl-Tetrahydro-Furan-2-Yl)-5-Methyl-1H-Pyrimidine-2,4-Dione, 1-[(3xi)-3-azido-2,3-dideoxy-beta-D-glycero-pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione, 3'-Azido-3'-Deoxythymidine, 3'-Azido-3'-desoxythymidine, 3'-Azido-3'-thymidine, 3'-Azidothymidine, 3'-Deoxy-3'-azidothymidine, 3-Azido-3-deoxy-thymidine, 3′-Azt, AZT, AZT (pharmaceutical), Azidothymidine, Azitidin, Bw-A 509U, Compound S, Nsc 602670, Retrovir, Retrovir IV, Retrovis, Thymidine, 3'-azido-3'-deoxy-, Timazid, Viro-Z, ZDV, ZVD, Zido-H, Zidovudine(AZT)

Description

Applications A potent and selective inhibitor of HIV-1 replication.
References Mitsuya, H., et al.: Nature, 325, 773 (1987), Brehm, J., et al.: Biochem., 47, 14020 (2008), Paredes, R., et al.: J. Virol., 83, 2038 (2009), Wan, J., et al.: J. Med. Chem., 52, 1144 (2009), Mainardes, R., et al.: J. Pharm. Sci., 98, 257 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 267.24
• Formula: C₁₀H₁₃N₅O₄
• Color/Form: White To Yellow
• InChI: InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
• SMILES: Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O