3'-Azido-3'-deoxythymidine, Methyl-d3

CAS: 30516-87-1

Ref. TR-A825002

Product Information

• Name: 3'-Azido-3'-deoxythymidine, Methyl-d3
• Synonyms: AZT-d3, Zidovudine-d3, Retrovis-d3, Timazid-d3, Retrovir-d3, NSC 602670-d3, 1-(3-Azido-2,3-Dideoxy-Beta-D-Ribofuranosyl)Thymine, 1-(3-azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-(3-azido-2,3-dideoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, 1-(4-Azido-5-Hydroxymethyl-Tetrahydro-Furan-2-Yl)-5-Methyl-1H-Pyrimidine-2,4-Dione, 1-[(3xi)-3-azido-2,3-dideoxy-beta-D-glycero-pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione, 3'-Azido-3'-Deoxythymidine, 3'-Azido-3'-desoxythymidine, 3'-Azido-3'-thymidine, 3'-Azidothymidine, 3'-Deoxy-3'-azidothymidine, 3-Azido-3-deoxy-thymidine, 3′-Azt, AZT, AZT (pharmaceutical), Azidothymidine, Azitidin, Bw-A 509U, Compound S, Nsc 602670, Retrovir, Retrovir IV, Retrovis, Thymidine, 3'-azido-3'-deoxy-, Timazid, Viro-Z, ZDV, ZVD, Zido-H, Zidovudine(AZT)

Description

Applications A deuterated, potent and selective inhibitor of HIV-1 replication.
References Mitsuya, H., et al.: Nature, 325, 773 (1987), Brehm, J., et al.: Biochem., 47, 14020 (2008), Paredes, R., et al.: J. Virol., 83, 2038 (2009), Wan, J., et al.: J. Med. Chem., 52, 1144 (2009), Mainardes, R., et al.: J. Pharm. Sci., 98, 257 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 270.26
• Formula: C₁₀H₁₀D₃N₅O₄
• Color/Form: Off White Solid
• SMILES: [2H]C([2H])([2H])c1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O