Berberine Hydrochloride-d6

CAS: 633-65-8

Ref. TR-B318152

Product Information

• Name: Berberine Hydrochloride-d6
• Synonyms: 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride-d6, Berberine Chloride-d6, 7,8,13,13a-Tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)berbinium Chloride-d6, NSC 646666-d6, 1,3-Benzodioxolo[5,6-A]Benzo[G]Quinolizinium, 5,6-Dihydro-9,10-Dimethoxy-, Hydrochloride (1:1), 16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride, Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride, Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1), Berberberberine hydrochloride n-hydrate, Berberine IR, Berberine chloride, Berberine hcl, Berberinium chloride, Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride, NSC 163088, NSC 646666, ine HCl

Description

Stability Hygroscopic
Applications Berberine Hydrochloride-d6 is labelled Berberine Hydrochloride (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);

• Brand: TRC

Chemical properties

• Molecular weight: 377.85
• Formula: C₂₀H₁₂D₆ClNO₄
• Color/Form: Neat
• SMILES: [2H]C([2H])([2H])Oc1ccc2cc3[n+](cc2c1OC([2H])([2H])[2H])CCc1cc2c(cc1-3)OCO2.[Cl-]