CAS 633-65-8
:Berberine hydrochloride
Description:
Berberine hydrochloride is a quaternary ammonium salt derived from the alkaloid berberine, which is found in various plants, including goldenseal and barberry. It is characterized by its bright yellow color and is known for its bitter taste. The substance is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Berberine hydrochloride exhibits a range of biological activities, including antimicrobial, anti-inflammatory, and antidiabetic properties, which have garnered interest in both traditional and modern medicine. Its mechanism of action involves the modulation of several cellular pathways, including those related to glucose metabolism and lipid regulation. Additionally, berberine has been studied for its potential effects on cardiovascular health and gut microbiota. Due to its diverse pharmacological effects, berberine hydrochloride is often used in dietary supplements and herbal remedies, although its use should be approached with caution due to potential interactions with other medications and side effects. Overall, berberine hydrochloride is a compound of significant interest in both research and therapeutic contexts.
Formula:C20H18ClNO4
InChI:InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;
InChI key:InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M
SMILES:O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC.[Cl-]
Synonyms:- 1,3-Benzodioxolo[5,6-A]Benzo[G]Quinolizinium, 5,6-Dihydro-9,10-Dimethoxy-, Hydrochloride (1:1)
- 16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride
- Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
- Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)
- Berberberberine hydrochloride n-hydrate
- Berberine IR
- Berberine chloride
- Berberine hcl
- Berberinium chloride
- Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride
- NSC 163088
- NSC 646666
- ine HCl
- Berberine hydrochloride
- Berberine chloride form,Natural Yellow18
- 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-berbiniuchlori
- Berberine chloride form
- Berberine chloride ,98%
- Kyoberin
- Berberine hydrochloride hydrate,97%
- Berberdine HCl
- BERBERINECHLORIDE(SH)
- 9,10-Dimethoxy-5,6-dihydro-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
- BERBERINE CHLORIDE(AHP)
- 9,10-Dimethoxy-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
- berberiniumchloride
- NATURAL YELLOW 18
- BERBERIN HCL
- UMBELLATINE
- TIMTEC-BB SBB006488
- LABOTEST-BB LT00440956
- C.I.Natural Yellow 18
- Berberine Chloride, JP
- 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE
- BBR
- BERBERINE HYDROCHLORIDE N-HYDRATE
- 7,8,13,13a-Tetradehydro-9,10-diMethoxy-2,3-(Methylenedioxy)berbiniuM Chloride
- Berberin chloride dihydrate
- Berberinehydrochloride，Berberine chloride form
- 3)benzodioxolo(5,6-a)quinolizinium,5,6-dihydro-9,10-dimethoxy-benzo(g)(c
- 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
- NATURAL YELLOW 18 CHLORIDE
- Berberine chloride (TN)
- CI 75160
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 19 products.
Berberine Chloride Hydrate
CAS:Formula:C20H18ClNO4·xH2OPurity:>98.0%(T)(HPLC)Color and Shape:White to Yellow to Orange powder to crystalineMolecular weight:371.82 (as Anhydrous)Berberine chloride
CAS:Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical rFormula:C20H18ClNO4Color and Shape:Yellow to orange, PowderMolecular weight:371.82Berberine chloride
CAS:Berberine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.Formula:C20H18ClNO4Purity:(HPLC) ≥95%Color and Shape:PowderMolecular weight:371.82Berberine chloride
CAS:Berberine chlorideFormula:C20H18NO4Purity:77.7%Color and Shape:WhiteMolecular weight:336.12358Berberine hydrochloride
CAS:Formula:C20H18ClNO4Purity:97%Color and Shape:SolidMolecular weight:371.8142Berberine chloride
CAS:Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.Formula:C20H18ClNO4Purity:99.47% - 99.93%Color and Shape:Yellow Crystalline PowderMolecular weight:371.80Berberine hydrochloride
CAS:Formula:C20H18ClNO4Purity:96.0 - 104.0 % (dried basis)Color and Shape:Yellow or orange powderMolecular weight:371.82Berberine hydrochloride
CAS:Berberine hydrochlorideFormula:C20H18ClNO4Purity:98%Color and Shape:SolidMolecular weight:371.81Berberine chloride (Standard)
CAS:Berberine chloride (Standard) is a reference standard for research and analysis in studies involving Berberine chloride. Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used orally for various fungal and parasitic infections and an anti-diarrheal.Formula:C20H18ClNO4Color and Shape:SolidMolecular weight:371.80Berberine Chloride
CAS:Controlled ProductFormula:C20H18NO4·ClColor and Shape:NeatMolecular weight:371.81Berberine chloride
CAS:Controlled ProductFormula:C20H18NO4·ClColor and Shape:NeatMolecular weight:371.81Berberine hydrochloride
CAS:Berberine hydrochloride (berberine), a natural plant alkaloid derived from Chinese herbal medicine, is characterized by diverse pharmacological effects, such as anticancer and lower elevated blood glucose, it can prevent adhesion by downregulating ICAM-1 and reduce inflammation by inhibiting the TAK1/JNK and TAK1/NF-κB signaling after abdominal surgery, which brings out a good therapeutic approach for the development of clinical application for postoperative abdominal adhesion and inflammation.Formula:C20H18ClNO4Purity:95%~99%Color and Shape:PowderMolecular weight:371.817Berberine Hydrochloride-d6
CAS:Controlled ProductStability Hygroscopic
Applications Berberine Hydrochloride-d6 is labelled Berberine Hydrochloride (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);Formula:C20H12D6ClNO4Color and Shape:NeatMolecular weight:377.85Berberine Chloride Hydrate
CAS:Controlled ProductStability Hygroscopic
Applications An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);Formula:C20H18NO4·ClColor and Shape:NeatMolecular weight:371.81Berberine hydrochloride
CAS:Formula:C20H18ClNO4Purity:95.0%Color and Shape:SolidMolecular weight:371.82Berberine chloride
CAS:Activates AMPK enzyme; anti-inflammatory; anti-diabeticFormula:C20H18NO4•ClPurity:Min. 95%Color and Shape:PowderMolecular weight:371.81 g/mol
