2,2-Bis-(4-hydroxyphenyl)hexafluoropropane

CAS: 1478-61-1

Ref. TR-B447290

Product Information

• Name: 2,2-Bis-(4-hydroxyphenyl)hexafluoropropane
• Synonyms: Phenol, 4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]di- (6CI,7CI), Phenol, 4,4'-[trifluoro-1-(trifluoromethyl)ethylidene]di- (8CI), 4,4'-[2,2,2-Trifluoro-1-(trifluoromethyl)ethylidene]bis[phenol], 1,1,1,3,3,3-Hexafluoro-2,2-bis(4-hydroxyphenyl)propane, 2,2-(4-Hydroxyphenyl)hexafluoropropane, 2,2-Bis(4-hydroxyphenyl)-1,1,1,3,3,3-hexafluoropropane, 2,2-Bis(4-hydroxyphenyl)perfluoropropane, 2,2-Bis(p-hydroxyphenyl)hexafluoropropane, 4,4'-(Hexafluoroisopropylidene)bisphenol, 4,4'-(Hexafluoroisopropylidene)diphenol, BIS-AF, BIS-AF(H), Biphenol AF, Bisphenol AE, Bisphenol AF, Cheminox BAF, Curative 30, GP 21, Hexafluorobisphenol A, Hexafluorodiphenylolpropane, Hexafluoroisopropylidenebis(4-hydroxybenzene), NSC 152522
• Brand: TRC

Description

Applications 2,2-Bis-(4-hydroxyphenyl)hexafluoropropane acts as an endocrine-disrupting chemical (EDC), activating estrogen through the estrogen receptor ERα. It is a full agonist for the estrogen receptor.
References Matsushima, A. et al.: Environ. Health, Perspect. 118, 1267 (2010);

Chemical properties

• Molecular weight: 336.23
• Formula: C₁₅H₁₀F₆O₂
• Color/Form: Neat
• InChI: InChI=1S/C15H10F6O2/c16-14(17,18)13(15(19,20)21,9-1-5-11(22)6-2-9)10-3-7-12(23)8-4-10/h1-8,22-23H
• InChI key: InChIKey=ZFVMWEVVKGLCIJ-UHFFFAOYSA-N
• SMILES: Oc1ccc(C(c2ccc(O)cc2)(C(F)(F)F)C(F)(F)F)cc1