Product Information
Name:BIX 01294
Controlled Product
Synonyms:
- 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine
Brand:TRC
Description:Applications BIX 01294 is a euchromatic histone-lysine N-methyltransferase 2 (EHMT2) inhibitor, induces autophagy and apoptosis in human neuroblastoma cells, specifically human bladder cancer cells.References Cui, J. et al.: Cancer Cell Int., 15, 1 (2015); Shin, J. et al.: Biochem. Biophys. Res. Comm., 350, 428 (2015);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:490.65
Formula:C28H38N6O2
Color/Form:Neat
InChI:InChI=1S/C28H38N6O2/c1-32-12-7-13-34(17-16-32)28-30-24-19-26(36-3)25(35-2)18-23(24)27(31-28)29-22-10-14-33(15-11-22)20-21-8-5-4-6-9-21/h4-6,8-9,18-19,22H,7,10-17,20H2,1-3H3,(H,29,30,31)
InChI key:InChIKey=OSXFATOLZGZLSK-UHFFFAOYSA-N
SMILES:COc1cc2nc(N3CCCN(C)CC3)nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC
Technical inquiry about: BIX 01294
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