Product Information
Name:BML-286
Controlled Product
Synonyms:
- 2-[[3-[(2-phenylacetyl)amino]benzoyl]amino]benzoic acid
Brand:TRC
Description:Applications A small molecule inhibitor of the PDZ domain of Dishevelled (Dvl): an essential protein in the Wnt signaling pathways. This compound reduced the levels of apoptosis in the hyaloid vessels of the eye and also suppressed the growth of prostate cancer PC-3 cells. It is a useful tool for studies dissecting the Wnt signaling pathways.References Grandy, D. et al.: J. Biol. Chem., 284, 24 (2009);
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Chemical properties
Molecular weight:374.389
Formula:C22H18N2O4
Color/Form:Neat
InChI:InChI=1S/C22H18N2O4/c25-20(13-15-7-2-1-3-8-15)23-17-10-6-9-16(14-17)21(26)24-19-12-5-4-11-18(19)22(27)28/h1-12,14H,13H2,(H,23,25)(H,24,26)(H,27,28)
InChI key:InChIKey=OBGIRQUECFHUEY-UHFFFAOYSA-N
SMILES:O=C(Cc1ccccc1)Nc1cccc(C(=O)Nc2ccccc2C(=O)O)c1
Technical inquiry about: BML-286
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