Product Information
Name:N-Boc-3-hydroxy-L-valine
Controlled Product
Synonyms:
- N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-threonine
- N-[(1,1-Dimethylethoxy)carbonyl]-3-hydroxy-L-valine
- (S)-2-(tert-Butoxycarbonylamino)-3-hydroxy-3-methylbutanoic Acid
Brand:TRC
Description:Applications N-Boc-3-hydroxy-L-valine is used as a reagent in the synthesis of metabolites of PPI-2458, which is a selective, irreversible inhibitor of methionine aminopeptidase-2 (MetAP2). N-Boc-3-hydroxy-L-valine is also used in the preparation of Boceprevir (B674500); an NS3 serine protease inhibitor of hepatitis C virus for the treatment of HCV infection.References Arico-Muendel, C.C., et al.: Drug Metab. Dispos., 41, 814 (2013); Venkatraman, S., et al.: J. Med. Chem., 49, 6074 (2006)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:233.26
Formula:C10H19NO5
Color/Form:Neat
InChI:InChI=1S/C10H19NO5/c1-9(2,3)16-8(14)11-6(7(12)13)10(4,5)15/h6,15H,1-5H3,(H,11,14)(H,12,13)/t6-/m1/s1
InChI key:InChIKey=SZVRVSZFEDIMFM-ZCFIWIBFSA-N
SMILES:CC(C)(C)OC(=O)N[C@H](C(=O)O)C(C)(C)O
Technical inquiry about: N-Boc-3-hydroxy-L-valine
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