tert-Butylhydroquinone

CAS: 1948-33-0

Ref. TR-B692950

Product Information

• Name: tert-Butylhydroquinone
• Synonyms: Hydroquinone, tert-butyl- (6CI,7CI,8CI), 2-(1,1-Dimethylethyl)-1,4-benzenediol, 2-(1,1-Dimethylethyl)hydroquinone, 2-(tert-Butyl)-p-hydroquinone, 2-t-Butylhydroquinone, 2-tert-Butyl-1,4-benzenediol, 2-tert-Butyl-1,4-dihydroxybenzene, 2-tert-Butyl-1,4-hydroquinone, 2-tert-Butyl-4-hydroxyphenol, 2-tert-Butylhydroquinone, Banox 20BA, Grindox 204, Grindox 450, Keniox 20, MC-TB 20, MTBHQ, Mono-tert-butylhydroquinone, Mono-tertiarybutylhydroquinone, NSC 4972, PI 172, Stearer TBH, TBHQ, Tenox 20, Tenox TBHQ, t-Butylhydroquinone, tert-Butyl-1,4-benzenediol, tert-Butyl-1,4-dihydroxybenzene, tert-Butyldihydroxybenzene
• Brand: TRC

Description

Applications tBHQ is an antioxidant in induction of AP-1, NF-κB, and glutathione S-transferase gene expression. It also disrupts ability of Kelch-like ECH-associated protein 1(Keap1) to target Nrf2, a bZIP transcription factor, for proteasome-mediated degradation and promote nuclear accumulation of Nrf2.
References Pinkus, R., et al.: J. Biol. Chem., 271, 13422 (1996); Zhang, D., et al.: Mol. Cell. Bio., 23, 8137 (2003)

Chemical properties

• Molecular weight: 166.22
• Formula: C₁₀H₁₄O₂
• Color/Form: Neat
• InChI: InChI=1S/C10H14O2/c1-10(2,3)8-6-7(11)4-5-9(8)12/h4-6,11-12H,1-3H3