Caffeic Acid Phenethyl Ester

CAS: 104594-70-9

Ref. TR-C080050

Product Information

• Name: Caffeic Acid Phenethyl Ester
• Synonyms: 2-phenylethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, 2-Phenylethyl 3-(3,4-Dihydroxyphenyl)-2-Propenoate, 2-Phenylethyl 3-(3,4-Dihydroxyphenyl)Prop-2-Enoate, 2-Phenylethyl caffeate, 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 2-phenylethyl ester, 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, Caffeic acid phenethylester, Phenethyl Caffeate, β-Phenylethyl caffeate

Description

Applications Cytotoxic agent against cancer cell lines. Inhibitor of ornithine decarboxylase and protein tyrosine kinase. Found to be a specific inhibitor of the nuclear transcription factor, NF-kB. It has also been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation.
References Grunberger, D., et al.: Experientia, 44, 230 (1988), Fesen, M.R., et al.: Biochem. Pharmacol., 48, 595 (1994), Su, Z.Z., et al.: Cancer Res., 54, 1865 (1994), Zheng, Z.S., et al.: Oncol. Res., 7, 445 (1995), Mirzoeva, O.K. and Calder, P.C.: Essent. Fatty Acids, 55, 441 (1996)

• Brand: TRC

Chemical properties

• Molecular weight: 284.31
• Formula: C₁₇H₁₆O₄
• Color/Form: Neat
• InChI: InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
• InChI key: InChIKey=SWUARLUWKZWEBQ-VQHVLOKHSA-N
• SMILES: O=C(/C=C/c1ccc(O)c(O)c1)OCCc1ccccc1