Product Information
Name:CAL-101
Controlled Product
Synonyms:
- Idelalisib
- CAL-101,4(3H)-Quinazolinone
- 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-
- 4(3H)-Quinazolinone
- 5-fluoro-3-phenyl-2-[(1S)-1-(1H-purin-6-ylamino)propyl]- (9CI)
- 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone
- Delalisib
- GS 1101
- N6-[(S)-1-(5-Fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl]adenine
- Zydelig
- GS-1101
- See more synonyms
Brand:TRC
Description:Applications CAL-101 is a PI3K/mTOR pathway inhibitor used in the treatment of myeloid leukemia through sensitizing the cells to combatting drugs. Potent PI3K-p110-delta inhibitor.References Airiau, K. et al.: Cell. Death. Dis., 4, e827 (2013); Kulesz-Martin, M. et al Canc. Biol. Ther., 14m 95 (2013);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:415.40
Formula:C22H18FN7O
Color/Form:Light Brown
InChI:InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1
InChI key:InChIKey=IFSDAJWBUCMOAH-UHFFFAOYSA-N
SMILES:CCC(Nc1ncnc2[nH]cnc12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1
Technical inquiry about: CAL-101
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