Canrenone

CAS: 976-71-6

Ref. TR-C175610

Product Information

• Name: Canrenone
• Synonyms: Spironolactone Imp. F (EP), Spironolactone USP Related Compound A (AS), Spironolactone USP RC A (AS), (2'R)-3',4'-Dihydro-5'H-spiro[androst-4,6-diene-17,2'-furan]-3,5'-dione, Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone, (17alpha)-, 17alpha-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone (6CI,7CI,8CI), Spiro[17H-cyclopenta[a]phenanthrene-17,2'(5'H)-furan], pregna-4,6-diene-21-carboxylic acid deriv., 11614 R.P., 17-Hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylic acid lactone, 17-Hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylic acid gamma-lactone, 17alpha-(2-Carboxyethyl)-17beta-hydroxyandrosta-4,6-dien-3-one lactone, 17beta-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid, 20-Spiroxa-4,6-diene-3,21-dione, 3-(17beta-Hydroxy-3-oxoandrosta-4,6-dien-17alpha-yl)propionic acid lactone, 3-(17beta-Hydroxy-3-oxoandrosta-4,6-dien-17alpha-yl)propionic acid gamma-lactone, 3-(3-Oxo-17beta-hydroxy-4,6-androstadien-17alpha-yl)propionic acid gamma-lactone, 3'-(3-Oxo-17beta-hydroxyandrosta-4,6-dien-17alpha-yl)-propionic acid lactone, Aldadiene, NSC 261713, Phanurane, SC 9376, Spirolactone SC 14266, Spironolactone Related Compound A, Spironolactone Impurity F, (10R,13S,17R)-10,13-dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione, (8R,9S,10R,13S,14S,17R)-10,13-dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione, 10,13-dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione, 11614 R. P., 17-Hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid lactone, 17-Hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid γ-lactone, 17alpha-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone (8CI), 17α-(2-Carboxyethyl)-17β-hydroxyandrosta-4,6-dien-3-one lactone, 17α-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, 17β-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid, 3-(17β-Hydroxy-3-oxoandrosta-4,6-dien-17α-yl)propionic acid lactone, 3-(17β-Hydroxy-3-oxoandrosta-4,6-dien-17α-yl)propionic acid γ-lactone, 3-(3-Oxo-17β-hydroxy-4,6-androstadien-17α-yl)propionic acid γ-lactone, 3′-(3-Oxo-17β-hydroxyandrosta-4,6-dien-17α-yl)-propionic acid lactone, Aldadiene (VAN), Brn 0046602, Canrenona, Canrenona [INN-Spanish], Canrenone [USAN:INN], Canrenonum, Canrenonum [INN-Latin], Luvion, Nsc 261713, Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone (17alpha)-, Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, (17α)-, Rp 11641, Sc 9376, Spiro[17H-cyclopenta[a]phenanthrene-17,2′(5′H)-furan], pregna-4,6-diene-21-carboxylic acid deriv., Unii-78O20X9J0U

Description

Impurity Spironolactone EP Impurity F
Applications Canrenone (Spironolactone EP Impurity F) is an aldosterone antagonist. Diuretic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sadee, W., et al.: J. Pharmacol. Exp. Ther., 185, 686 (1973), Pitt, B., et al.: Circulation, 108, 1831 (2003), Silvestre, J., et al.: J. Biol. Chem., 273, 4883 (1998), Struthers, A., et al.: Heart, 92, 1728 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 340.46
• Formula: C₂₂H₂₈O₃
• Color/Form: Light Yellow Solid
• InChI: InChI=1S/C22H28O3/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21)12-8-19(24)25-22/h3-4,13,16-18H,5-12H2,1-2H3/t16-,17+,18+,20+,21+,22-/m1/s1
• InChI key: InChIKey=UJVLDDZCTMKXJK-WNHSNXHDSA-N
• SMILES: C[C@]12CC[C@H]3[C@@H](C=CC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@]21CCC(=O)O1