Product Information
Name:CHIR 99021 Hydrochloride Salt
Controlled Product
Synonyms:
- 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile
Brand:TRC
Description:Applications CHIR 99021 Hydrochloride is an inhibitor of glycogen synthase kinase 3, which mimics Wnt signaling in preadipocytes. CHIR 99021 stabilizes free cytosolic β-catenin and inhibits adipogenesis by blocking induction of CCAAT/enhancer-binding protein α and peroxisome proliferator-activated receptor γ. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Bennett, C., et al.: J. Bio. Chem., 277, 30998 (2002);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:465.343646
Formula:C22H18Cl2N8•xHCl
Color/Form:Neat
InChI:InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32)
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