Chloramphenicol

CAS: 56-75-7

Ref. TR-C325030

Product Information

• Name: Chloramphenicol
• Synonyms: Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-, Levomycetin (7CI), Ak-Chlor, Alficetyn, Amphenicol, Amphicol, Amseclor, Anacetin, Aquamycetin, Austracol, CAF, CAF (pharmaceutical), CAM, CAP, CPh, Catilan, Chemicetin, Chemicetina, Chlomycol, Chloramex, Chloramsaar, Chlorasol, Chlorcetin, Chloricol, Chlorocaps, Chlorocid, Chlorocide, Chlorocidin C, Chlorocidin C tetran, Chlorocin, Chloromycetin, Chloronitrin, Chloroptic, Ciplamycetin, Cloramfen, Cloramficin, Cloramicol, Clorocyn, Cloromisan, Cylphenicol, D-(-)-Chloramphenicol, D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol, D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol, D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol, D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol, D-(-)-threo-Chloramphenicol, D-Chloramphenicol, D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol, D-threo-Chloramphenicol, D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol, Detreomycin, Embacetin, Enicol, Enteromycetin, Farmicetina, Fenicol, Globenicol, Gloveticol, Halcetin, I 337A, Intramycetin, Ismicetina, Juvamycetin, Kamaver, Kemicetine, Klorita, Klorocid S, Leukomyan, Leukomycin, Levocin, Levomicetina, Levomitsetin, Levoplast, Levosin, Levovetin, Loromisin, Mastiphen, Micloretin, Micoclorina, Microcetina, Mychel, Mychel-Vet, Mycinol, Myclocin, NSC 3069, Normimycin V, Novomycetin, Ocuphenicol, Opclor, Ophthochlor, Pantovernil, Paraxin, Quemicetina, Ronphenil, Septicol, Sintomicetin, Sintomicetina, Sintomicetine R, Sno Phenicol, Soluthor, Stanomycetin, Synthomycetin, Tevcocin, Tifomycine, Treomicetina, Unimycetin, Veticol, Viceton, Mycochlorin, Acetamide, 2,2-dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)- (8CI), 2,2-Dichloro-N-(2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl)-Acetamid, 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, 2,2-Dichloro-N-[2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide, 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, 2,2-dichloro-N-[(1R,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide, 2,2-dichloro-N-[(1S,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide, Bradyoxetin, Cloramfenicol, D-(-)-Threo-2,2-Dichloro-N-[Beta-Hydroxy-Alpha-(Hydroxy-Methyl)-P-Nitrophenethyl]Acetamide, Levomycetin, Synthomycin, [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide

Description

Applications Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

• Brand: TRC

Chemical properties

• Molecular weight: 323.13
• Formula: C₁₁H₁₂Cl₂N₂O₅
• Color/Form: White To Light Yellow
• InChI: InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1
• SMILES: O=C(N[C@H](CO)[C@H](O)c1ccc([N+](=O)[O-])cc1)C(Cl)Cl