Chlorambucil

CAS: 305-03-3

Ref. TR-C325050

Product Information

• Name: Chlorambucil
• Synonyms: Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-, Butyric acid, 4-[p-[bis(2-chloroethyl)amino]phenyl]- (8CI), 4-[Bis(2-chloroethyl)amino]benzenebutanoic acid, 4-[p-[Bis(2-chloroethyl)amino]phenyl]butyric acid, Ambochlorin, Amboclorin, CB 1348, Chloraminophene, Chlorbutin, Chlorobutine, Ecloril, Leukeran, Leukeran Tablets, Linfolizin, Linfolysin, Lympholysin, NCI 3088, NSC 3088, gamma-[p-Bis(2-chloroethyl)aminophenyl]butyric acid, gamma-[p-Di(2-chloroethyl)aminophenyl]butyric acid, 4-(P-Bis(2-Chloroethyl)Aminophenyl)Butyric Acid, 4-(P-Bis(Beta-Chloroethyl)Aminophenyl)Butyric Acid, 4-(p-(N,N-Di-2-chloroethyl)aminophenyl)butyric acid, 4-(p-N,N-Di-(beta-chloroethyl)aminophenyl)butyric acid, 4-[4-[3-Chloro-1-(2-Chloroethyl)Propyl]Phenyl]Butanoic Acid, 4-[Bis(2-Chloroethyl)Amino]Benzenebutanoic Acid, 4-[Bis(2-chloroethyl)aminophenyl]butyric acid, 4-{4-[Bis(2-Chloroethyl)Amino]Phenyl}Butanoic Acid, Benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]-, Butanoic acid, 4-[bis(2-chloroethyl)amino]benzene, Butyric acid, 4-[p-[bis(2-chloroethyl)amino]phenyl]-, Cb 1348, Cb l348, Chloraminophen, Chloroambucil, Chlorobutin, Clorambucilo, Elcoril, Gamma-(P-Bis(2-Chloroethyl)Aminophenyl)Butyric Acid, Leukersan, Leukoran, N,N-Di-(2-chloroethyl)-gamma-(p-aminophenyl)butyric acid, Nci 3088, Nsc 3088, Phenylbutyric acid nitrogen mustard, γ-[p-Bis(2-chloroethyl)aminophenyl]butyric acid, γ-[p-Di(2-chloroethyl)aminophenyl]butyric acid

Description

Applications Chlorambucil is a alkylating agent that is used as an chemotherapy drug in the treatment of chronic lymphocytic leukemia. Chlorambucil is also used to treat non-Hodgkin's lymphoma (NHL) and Hodgkin's disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cogia, A., et al.: Leuk. Lymph., 53, 1961 (2012); Tonino, S.H., et al.: Leuk. Lymph., 53, 1785 (2012); Smolej, L., et al.: Curr. Pharma. Design., 18, 3399 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 304.21
• Formula: C₁₄H₁₉Cl₂NO₂
• Color/Form: Neat
• InChI: InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
• InChI key: InChIKey=JCKYGMPEJWAADB-UHFFFAOYSA-N
• SMILES: O=C(O)CCCc1ccc(N(CCCl)CCCl)cc1