TR-C363085 - n-chloro-nn-dimethyl-sulfamide | 802565-11-3

Sulfamide (Sulfuric diamide) is used in organic chemistry for synthesis.

<p>Applications A carbonic anhydrase inhibitor; used for treatment of cancer.<br>References Sterling, D., et al.: J. Biol. Chem., 276, 47886 (2001), Hilvo, M., et al.: Biochem. J., 392, 83 (2005), Innocenti, A., et al.: Bioorg. Med. Chem. Lett., 15, 1909 (2005), Cerghet, M., et al.: J. Neurosci., 26, 1439 (2006),<br></p>

<p>Sulfamide is a pharmacological agent that inhibits the growth of bacteria. Sulfamide has been shown to be reactive with hydrogen fluoride, which may result in the formation of sulfamoyl chloride. This reactive form of sulfamide may react with other compounds and cause unwanted side-effects. <br>Sulfamides are used for the treatment of infectious diseases such as pneumonia and urinary tract infections, as well as for the treatment of other conditions like congestive heart failure and rheumatoid arthritis. They work by inhibiting enzymes necessary for bacterial growth, including target enzymes such as dihydropteroate synthase, which is involved in folate synthesis. Sulfamides also have inhibitory properties on human osteosarcoma cell proliferation.</p>

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

<p>Applications N,N-Diphenyl Sulfamide is used in the preparation of aryl-substituted sulfamides.<br>References Muniz, K. et al.: Synlett 1, 149 (2005);<br></p>

<p>It is employed as a carbonic anhydrase inhibitor. It is widely used as a pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesa</p>

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi