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(3S)-4-Chloro-3-hydroxybutyronitrile

CAS:

Ref. TR-C366605

1g
188.00€
10g
251.00€
100g
598.00€
(3S)-4-Chloro-3-hydroxybutyronitrile
TRC

Product Information

Name:(3S)-4-Chloro-3-hydroxybutyronitrile
Controlled Product
Synonyms:
  • (3S)-4-Chloro-3-hydroxybutanenitrile
  • (S)-4-Chloro-3-hydroxybutanenitrile
  • (S)-(-)-4-Chloro-3-hydroxybutyronitrile
  • (S)-4-Chloro-3-hydroxybutyronitrile
Brand:TRC
Description:Applications (3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparation of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.References Kanno, O. et al.: Hetero., 53, 173 (2000); Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006); Jiang, C. et al.: Lett. Org. Chem., 9, 520 (2012);
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Chemical properties

Molecular weight:119.55
Formula:C4H6ClNO
Color/Form:Neat
InChI:InChI=1S/C4H6ClNO/c5-3-4(7)1-2-6/h4,7H,1,3H2/t4-/m0/s1
InChI key:InChIKey=VNBFUGOVQMFIRN-BYPYZUCNSA-N
SMILES:N#CC[C@H](O)CCl

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