Product Information
Name:(3S)-4-Chloro-3-hydroxybutyronitrile
Controlled Product
Synonyms:
- (3S)-4-Chloro-3-hydroxybutanenitrile
- (S)-4-Chloro-3-hydroxybutanenitrile
- (S)-(-)-4-Chloro-3-hydroxybutyronitrile
- (S)-4-Chloro-3-hydroxybutyronitrile
Brand:TRC
Description:Applications (3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparation of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.References Kanno, O. et al.: Hetero., 53, 173 (2000); Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006); Jiang, C. et al.: Lett. Org. Chem., 9, 520 (2012);
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Chemical properties
Molecular weight:119.55
Formula:C4H6ClNO
Color/Form:Neat
InChI:InChI=1S/C4H6ClNO/c5-3-4(7)1-2-6/h4,7H,1,3H2/t4-/m0/s1
InChI key:InChIKey=VNBFUGOVQMFIRN-BYPYZUCNSA-N
SMILES:N#CC[C@H](O)CCl
Technical inquiry about: (3S)-4-Chloro-3-hydroxybutyronitrile
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