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Product Information
- Piperazine
- 1-(3-chlorophenyl)-
- Piperazine
- 1-(m-chlorophenyl)- (8CI)
- 1-(m-Chlorophenyl)piperazine
- 4-(3-Chlorophenyl)piperazine
- N-(3-Chlorophenyl)piperazine
- N-(m-Chlorophenyl)piperazine
- NSC 49307
- m-CPP
- See more synonyms
- mCPP
- mCPP (pharmaceutical)
- meta-Chlorophenylpiperazine
- 1-(3-Chlorphenyl)-piperazine
- 1-(M-Chlorophenyl)Piperazine
- 1-(M-Clorofenil)Piperazina
- 1-(m-Chlorphenyl)piperazin
- 3-Chlorophenyl piperazine
- 3-Chlorphenylpiperazine
- Nsc 49307
- Piperazine, 1-(3-chlorophenyl)-
- Piperazine, 1-(m-chlorophenyl)-
Applications It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.
References (1) Bo Wen, et al.: Drug Metab. Dispos., 36, 841 (2008) (2) Maes, M., et al.: J. Clin. Psychopharmacol., 17, 358 (1997) (3) Fiorella, D., et al.: Psychopharmacology, 119, 220 (1995)
Chemical properties
Technical inquiry about: TR-C379590 1-(3-Chlorophenyl)piperazine
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