Product Information
Name:Clotiazepam
Controlled Product
Synonyms:
- 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2H-thieno[2,3-e]-1,4-diazepin-2-one
- 2H-Thieno[2,3-e]-1,4-diazepin-2-one
- 5-(o-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl- (8CI)
- 1-Methyl-5-o-chlorophenyl-7-ethyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-one
- 5-(2-Chlorophenyl)-7-ethyl-1-methyl-1H-thieno[2,3-e][1,4]diazepin-2(3H)-one
- 5-(o-Chlorophenyl)-7-ethyl-1-methyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-one
- Clozan
- Rize
- Rizen
- Tienor
- Trecalmo
- Veratran
- See more synonyms
Brand:TRC
Description:
Applications A thienodiazepine derivative that possesses anxiolytic, skeletal muscle relaxant anticonvulsant, sedative properties as well as contributing to siginificant increase stage 2 NREM sleep. It binds to benzodiazepine site of the GABAA receptor where it acts as a full agonist resulting in enhanced GABA inhibitory effect at the GABAA receptor. Controlled Substance.
References Mandrioli, R. et al.: Curr.Drug Metab., 8, 827 (2008); Nakazawa, Y. et al.: Psychopharmacol., 44, 165 (1975); Yakushiji, T. et al.: Br. J. Pharmacol., 98, 735 (1989);
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Chemical properties
Molecular weight:318.82
Formula:C16H15ClN2OS
Color/Form:Neat
InChI:InChI=1S/C16H15ClN2OS/c1-3-10-8-12-15(11-6-4-5-7-13(11)17)18-9-14(20)19(2)16(12)21-10/h4-8H,3,9H2,1-2H3
InChI key:InChIKey=CHBRHODLKOZEPZ-UHFFFAOYSA-N
SMILES:CCc1cc2c(s1)N(C)C(=O)CN=C2c1ccccc1Cl
Technical inquiry about: Clotiazepam
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