Estimated delivery in United States, on Tuesday 17 Dec 2024
Product Information
Name:
CP-10447
Synonyms:
- 4(3H)-Quinazolinone
- 3-(4-bromo-2-methylphenyl)-2-methyl-
- 4(3H)-Quinazolinone
- 3-(4-bromo-o-tolyl)-2-methyl- (6CI,7CI,8CI)
- 4(3H)-Quinazolinone,3-(4-bromo-o-tolyl)-2-methyl- (6CI,7CI,8CI)
- Cp 10447
Description:
Applications CP-10447 is an inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly.
References Haghpassand, M. et al.: J. Lipid. Res., 37, 1468 (1996); Pan, M. et al.: J. Biol. chem., 275, 27399 (2000);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
329.19
Formula:
C16H13BrN2O
Color/Form:
Neat
InChI:
InChI=1S/C16H13BrN2O/c1-10-9-12(17)7-8-15(10)19-11(2)18-14-6-4-3-5-13(14)16(19)20/h3-9H,1-2H3
InChI key:
InChIKey=CIYGULLCDQXZNK-UHFFFAOYSA-N
SMILES:
Cc1cc(Br)ccc1-n1c(C)nc2ccccc2c1=O
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-C781200 CP-10447
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