Product Information
Name:CP-10447
Synonyms:
- 4(3H)-Quinazolinone
- 3-(4-bromo-2-methylphenyl)-2-methyl-
- 4(3H)-Quinazolinone
- 3-(4-bromo-o-tolyl)-2-methyl- (6CI,7CI,8CI)
Brand:TRC
Description:Applications CP-10447 is an inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly.References Haghpassand, M. et al.: J. Lipid. Res., 37, 1468 (1996); Pan, M. et al.: J. Biol. chem., 275, 27399 (2000);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:329.19
Formula:C16H13BrN2O
Color/Form:Neat
InChI:InChI=1S/C16H13BrN2O/c1-10-9-12(17)7-8-15(10)19-11(2)18-14-6-4-3-5-13(14)16(19)20/h3-9H,1-2H3
InChI key:InChIKey=CIYGULLCDQXZNK-UHFFFAOYSA-N
SMILES:Cc1cc(Br)ccc1-n1c(C)nc2ccccc2c1=O
Technical inquiry about: CP-10447
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