Cyclophosphamide Monohydrate

CAS: 6055-19-2

Ref. TR-C988580

Product Information

• Name: Cyclophosphamide Monohydrate
• Synonyms: 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide monohydrate, Cyclophosphamide hydrate, Endoxan monohydrate, (2R)-N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide, (2S)-N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide, 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, hydrate (1:1), 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate, Cyclophosphamide Isopac Monohydrate, Cyclophosphamide Sterile monohydrate, Cyclophosphane monohydrate, Kgyclophosphamide monohydrate, N,N-bis(2-chloroethyl)-1-oxo-6-oxa-2-aza-1$l5-phosphacyclohexan-1-amine hydrate

Description

Applications It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999),

• Brand: TRC

Chemical properties

• Molecular weight: 279.10
• Formula: C₇H₁₅Cl₂N₂O₂P·H₂O
• Color/Form: Neat
• InChI: InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• InChI key: InChIKey=PWOQRKCAHTVFLB-UHFFFAOYSA-N
• SMILES: O.O=P1(N(CCCl)CCCl)NCCCO1