Product Information
Name:Trametinib-13C6
Controlled Product
Synonyms:
- G 02442104-13C6
- GSK 1120212-13C6
- JTP 74057-13C6
- N-[3-[3-Cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethy-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide-13C6
- N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide-13C6
Brand:TRC
Description:Applications Trametinib-13C6 is the labelled compound form of Trametinib (C988930), which is used in the systematic treatment of advanced cutaneous melanoma. An EGFR kinase inhibitor and potent MEK inhibitor.References Ercan, D., et al.: Canc. Disc., 2, 934 (2012); Mackiewicz-Wysocka, M., et al.: Exp. Opin. Investig. Drugs., 22, 181 (2013);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:621.351
Formula:C6C20H23FIN5O4
Color/Form:Neat
InChI:InChI=1S/C26H23FIN5O4/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34)/i4+1,5+1,6+1,12+1,16+1,18+1
InChI key:InChIKey=LIRYPHYGHXZJBZ-YGELHQHLSA-N
SMILES:CC(=O)N[13c]1[13cH][13cH][13cH][13c](-n2c(=O)n(C3CC3)c(=O)c3c(Nc4ccc(I)cc4F)n(C)c(=O)c(C)c32)[13cH]1
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