Dapsone

CAS: 80-08-0

Ref. TR-D193250

Product Information

• Name: Dapsone
• Synonyms: Sulfacetamide Sodium Imp. D (EP), Sulfacetamide Imp. D (EP), 4,4'-sulfonyldianiline, Benzenamine, 4,4'-sulfonylbis-, Aniline, 4,4'-sulfonyldi- (7CI,8CI), 1,1'-Sulfonylbis[4-aminobenzene], 1358F, 4,4'-DDS, 4,4'-Dapsone, 4,4'-Diaminodiphenyl sulfone, 4,4'-Sulfonylbisaniline, 4,4'-Sulfonylbisbenzamine, 4,4'-Sulfonyldianiline, 4,4'-Sulfonyldiphenylamine, 4,4'-Sulphonyldianiline, 4-(4-Aminophenylsulfonyl)benzenamine, 4-Aminophenyl sulfone, Aczone, Aradur 9664-1, Aradur 976-1, Araldite HT 976, Atrisone, Avlosulfon, Avlosulfone, Bis(4-aminophenyl) sulfone, Bis(p-aminophenyl) sulfone, Croysulfone, DADFS, DADPS, DDS, DDS (pharmaceutical), DSS, Dapson, Di(4-aminophenyl)sulfone, Di(p-aminophenyl) sulfone, Diaphenylsulfon, Diaphenylsulfone, Diphenasone, Diphone, Disulone, Dumitone, Eporal, F 1358, HB-MC-GE 40, HB-MC-GE 45, HT 9664, HT 976, HT 976-1, HY 976, Hardener HT 976, Lapox K 10, Metabolite C, NSC 6091, Novophone, Seikacure S, Servidapson, Sulfona, Sulfona-Mae, Sulphadione, Sumicure S, Udolac, p,p'-Diaminodiphenyl sulfone, p,p'-Sulfonyldianiline, p-Aminophenyl sulfone, 4-Aminophenyl Sulfone, 4,4'-Sulfonyldianiline, Sulfacetamide Sodium Impurity D, Sulfacetamide Impurity D, 4,4'-Dds, 4,4'-Diamino Diphenyl Sulfone, 4,4'-Diamino Diphenyl Sulphone, 4,4'-Diaminodiphenylsulfon, 4,4'-Diaminodiphenylsulfone, 4,4-Diaminodiphenyl sulfone, 4,4-Diaminodiphenyl sulphone, 4,4-Sulfonyldianiline, 4,4-Sulphonyldianiline, 4,4′-Diaminobiphenyl sulfone, 4,4′-Sulfonylbis[benzenamine], 4-((4-Aminophenyl)Sulfonyl)Phenylamine, 4-(4-Aminophenyl)sulfonylaniline, 4-Aminophenyl sulphone, 44Dds, Aniline, 4,4'-sulfonyldi-, Aradur 9664-1NL, Aradur 976, Aradur 9761-1, Avlosulphone, Benzenamine, 4,4'-sulfonylbis-, Bis(P-Aminophenyl)Sulfone, Croysulphone, D 0089, Dadfs, Dadps, Di(4-Aminophenyl) Sulphone, Diaminodiphenylsulfone, Diphenyl Sulfone, 4,4'-Diamino-, Hb-Mc-Ge 40, Hb-Mc-Ge 45, Hew 62, Ht 9664, Ht 976, Ht 976-1, Hy 976, Nsc 6091, P,P'-Sulfonyldianiline, P-Aminophenyl Sulfone, Timtec-Bb Sbb003168

Description

Applications An antibacterial used in the treatment of dermatitis herpetiformis.
References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 248.30
• Formula: C₁₂H₁₂N₂O₂S
• Color/Form: White
• InChI: InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
• InChI key: InChIKey=MQJKPEGWNLWLTK-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)c2ccc(N)cc2)cc1