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De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
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De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride

CAS: 1000690-91-4

Ref. TR-D215505

Estimated delivery in United States, on Monday 14 Dec 2020

Product Information

Name:
De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
Synonyms:
  • 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineacetic Acid Dihydrochloride
Description:

Applications De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, is an impurity of Cetirizine (C281100, 2HCl); a nonsedating type histamine H1-receptor antagonist and a major metabolite of Hydroxyzine (H996500). Pharmacological activity of Cetirizine resides primarily in the (R)-isomer. Also antihystaminic.
References De Vos, C., et al.: Ann. Allergy, 59, 278 (1987); Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987); Fadel, R., et al.: Clin. Allergy, 17, 373 (1987); Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)

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Chemical properties

Molecular weight:
344.8423646
Formula:
C19H21ClN2O2•2HCl
Color/Form:
White to Pale Beige Solid
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Hazard Info

UN Number:
EQ:
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