CAS 1000690-91-4

Cetirizine Impurity B dihydrochloride

CAS: 1000690-91-4

Cetirizine Impurity B dihydrochloride

Purity: ≥95%

Molecular weight: 417.76g/mol

Ref: 54-BUP11149

Cetirizine EP Impurity B DiHCl

CAS: 1000690-91-4

Formula: C₁₉H₂₁ClN₂O₂·2HCl

Color and Shape: White To Off-White Solid

Molecular weight: 344.84 2*36.46

Ref: 4Z-C-209

(RS)-2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]acetic Acid Dihydrochloride

CAS: 1000690-91-4

Color and Shape: Neat

Ref: 86-MM0380.02

Cetirizine Impurity B dihydrochloride

CAS: 1000690-91-4

Cetirizine Impurity B dihydrochloride is a Cetirizine antihistamine byproduct with anti-allergic properties.

Formula: C₁₉H₂₃Cl₃N₂O₂

Purity: 99.24%

Color and Shape: Solid

Molecular weight: 417.76

Ref: TM-T9084

De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride

Controlled Product

CAS: 1000690-91-4

Applications De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, is an impurity of Cetirizine (C281100, 2HCl); a nonsedating type histamine H1-receptor antagonist and a major metabolite of Hydroxyzine (H996500). Pharmacological activity of Cetirizine resides primarily in the (R)-isomer. Also antihystaminic. References De Vos, C., et al.: Ann. Allergy, 59, 278 (1987); Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987); Fadel, R., et al.: Clin. Allergy, 17, 373 (1987); Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)

Formula: C₁₉H₂₁ClN₂O₂•2HCl

Color and Shape: White

Molecular weight: 417.76

Ref: TR-D215505

Cetirizine impurity B dihydrochloride

CAS: 1000690-91-4

Cetirizine impurity B dihydrochloride is a minor impurity of cetirizine, which is a non-sedating antihistamine. The purity of the compound was determined by high performance liquid chromatography (HPLC) and its bioequivalence to cetirizine was assessed in a population pharmacokinetic study. Cetirizine impurity B dihydrochloride has been shown to have a similar pharmacokinetic profile to cetirizine and can be used as an alternative for the treatment of allergic rhinitis.

Formula: C₁₉H₂₁ClN₂O₂•(HCl)₂

Purity: Min. 90 Area-%

Color and Shape: Powder

Molecular weight: 417.76 g/mol

Ref: 3D-IC46026