Dehydro Indapamide

CAS: 63968-75-2

Ref. TR-D229660

Product Information

• Name: Dehydro Indapamide
• Synonyms: Indapamide Imp. B (EP), Indapamide USP Related Compound A, Indapamide USP RC A, 4-Chloro-N-(2-methyl-1H-indol-1-yl)-3-sulphamoylbenzamide, Indapamide Related Compound A, Indapamide Impurity B

Description

Impurity Indapamide USP Related Compound A/ Indapamide EP Impurity B
Applications A metabolite of Indapamide (M5). A dehydrogenation pathway by cytochromes P450. Indapamide USP Related Compound A
References Tamura A., et al.: Chem. Pharm. Bull., 38, 225 (1990), Harlow, G.R., et al.: J. Biol. Chem., 272, 5396 (1997), Ozden, T., et al.: Pharm. Pharmacol. Commun., 4, 397 (1998), Gruciani, G., et al.: J. Med. Chem., 48, 6970 (2005), Sun, H., et al.: Drug. Metab. Dispos., 37, 672 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 363.82
• Formula: C₁₆H₁₄ClN₃O₃S
• Color/Form: White To Light Brown
• InChI: InChI=1S/C16H14ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-9H,1H3,(H,19,21)(H2,18,22,23)
• InChI key: InChIKey=LWCDXWWLUHMMJI-UHFFFAOYSA-N
• SMILES: Cc1cc2ccccc2n1NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1