Product Information
Name:Deoxynivalenol
Controlled Product
Synonyms:
- (3α,7α)-12,13-Epoxy-3,7,15-trihydroxytrichothec-9-en-8-one
- Spiro[2,5-methano-1-benzoxepin-10,2'-oxirane]
- trichothec-9-en-8-one deriv.
- 4-Deoxynivalenol
- 4-Desoxynivalenol
- DON
- Dehydronivalenol
- NSC 269144
- Vomitoxin
Brand:TRC
Description:Applications Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus.Environmental contaminants; Food contaminants Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Bae, et al.: Toxicol. Sci., 105, 59 (2008), Shi, et al.: Toxicol. Sci., 109, 247 (2009), Krishnaswamy, et al.: Free Radic. Biol. Med., 49 50 (2010),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:296.32
Formula:C15H20O6
Color/Form:Neat
InChI:InChI=1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1
InChI key:InChIKey=LINOMUASTDIRTM-QGRHZQQGSA-N
SMILES:CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O
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