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N-Desmethyl Apalutamide

CAS:

Ref. TR-D291395

10mg
1,187.00€
25mg
2,223.00€
2500µg
343.00€
N-Desmethyl Apalutamide
TRC

Product Information

Name:N-Desmethyl Apalutamide
Controlled Product
Synonyms:
  • 4-[7-[6-Cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-benzamide,4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluorobenzamide
Brand:TRC
Description:Applications N-Desmethyl Apalutamide has been exploresd asthiohydantion androgen receptor antagonist for treament of cancerReferences Bignan, G.C. PCT Int. Appl. (2018), WO 2018037342 A1 20180301.
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Chemical properties

Molecular weight:463.41
Formula:C20H13F4N5O2S
Color/Form:Neat
InChI:InChI=1S/C20H13F4N5O2S/c21-14-7-10(2-3-12(14)16(26)30)29-18(32)28(17(31)19(29)4-1-5-19)11-6-13(20(22,23)24)15(8-25)27-9-11/h2-3,6-7,9H,1,4-5H2,(H2,26,30)
SMILES:N#Cc1ncc(N2C(=O)C3(CCC3)N(c3ccc(C(N)=O)c(F)c3)C2=S)cc1C(F)(F)F

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